Clinical Trials

Current Enrolling Trials

For more information on any of the studies listed below, please e-mail research@metrogr.org.

COVID-19

Expanded Access to Convalescent Plasma for the Treatment of Patients with COVID-19
Condition: Severe or life threatening COVID-19 infection
The purpose of this study is to grant access to potentially beneficial convalescent plasma to adult patients diagnosed with SARS-CoV-2 (COVID-19).
Investigators: Eric Feucht, MD; Jeffrey Fletcher, MD
Find this study on clinicaltrials.gov: https://clinicaltrials.gov/ct2/show/NCT04338360?term=04338360&draw=2&rank=1

CANCER

Metro Health – University of Michigan Health is a member of the Cancer Research Consortium of West Michigan (CRCWM).  Visit www.crcwm.org for a listing of available clinical trials.

NEURORADIOLOGY

ASPIRE: Anticoagulation in Intracerebral Hemorrhage (ICH) Survivors for Stroke Prevention and Recovery
Condition: Intracerebral hemorrhage and Non-Lobar Atrial Fibrillation
The purpose of this study is to determine if apixiban is superior to aspirin for the prevention of the composite outcomes of a stroke in patients with recent intracerebral hemorrhage (ICH) and atrial fibrillation (AF).
Investigators: Augusto Elias, MD; Jeffrey Fletcher, MD
Find this study on clinicaltrials.gov: https://clinicaltrials.gov/ct2/show/NCT03907046?term=Anticoagulation+in+Intracerebral+Hemorrhage+%28ICH%29+Survivors+for+Stroke+Prevention+and+Recovery&draw=2&rank=1

SATURN: Statins Use in Intracerebral Hemorrhage Patients
Condition: Intracerebral hemorrhage on statin therapy
The purpose of this study is to determine whether continuation vs. discontinuation of statin drugs is the best strategy after a lobar intracerebral hemorrhage (ICH).
Investigators: Augusto Elias, MD; Jeffrey Fletcher, MD
Find this study on clinicaltrials.gov: https://clinicaltrials.gov/ct2/show/NCT03936361?term=saturn&draw=2&rank=6

PERIPHERAL ARTERY DISEASE

LUTONIX BTK
Condition: Peripheral Artery Disease (PAD)
The goal of this research is to learn more about the benefits of using the Lutonix Drug-Coated Balloon catheter (formerly, Moxy Drug-Coated Balloon catheter) and to gather more data to show it’s safe when treating people with narrowed leg blood vessels.
Principal Investigator: Larry Diaz, MD
Find this study on clinicaltrials.gov: https://clinicaltrials.gov/ct2/show/NCT01870401?term=lutonix+btk&rank=1

PRIME Registry
Condition: Peripheral Artery Disease (PAD)
The purpose of this research is to evaluate immediate and long-term outcomes of endovascular revascularization in patients with Critical Limb Ischemia (CLI) and advanced PAD.
Principal Investigator: Larry Diaz, MD
Find this study on clinicaltrials.gov: https://clinicaltrials.gov/ct2/show/NCT02786173?term=PRIME&rank=5

HEART DISEASE

APPRAISE: Assessment of Primary Prevention Patients Receiving An ICD – Systematic Evaluation of ATP
Condition: Fast or Irregular Heart Rhythms
The purpose of this research is to understand the role of antitachycardia pacing (ATP) in patients receiving ICD therapy.
Principal Investigator: Matthew Sevensma, DO
Find this study on clinicaltrials.gov: https://clinicaltrials.gov/ct2/show/NCT02923726?term=Assessment+of+Primary+Prevention+Patients+Receiving+An+ICD+-+Systematic+Evaluation+of+ATP&draw=2&rank=1

BIOLIBRA Registry: AnaLysIs of Both Sex and Device Specific FactoRs on Outcomes in PAtients with Non-Ischemic Cardiomyopathy
Condition: Fast or Irregular Heart Rhythms
The purpose of this research is to confirm the long-term safety and reliability of the BIOTRONIK ICD or CRT-D.
Principal Investigator: Matthew Sevensma, DO
Find this study on clinicaltrials.gov: https://clinicaltrials.gov/ct2/show/NCT03884608?term=AnaLysIs+of+Both+Sex+and+Device+Specific+FactoRs+on+Outcomes+in+PAtients+with+Non-Ischemic+Cardiomyopathy&draw=2&rank=1

CHEETAH: A Prospective, Multicenter Study to Evaluate the Safety and Performance of the CAT RX Aspiration Catheter in Patients with a High Thrombus Burden Acute Coronary Vessel Occlusion
Condition: Heart Attack
The purpose of this research is to confirm the safety and performance of the CAT RX Aspiration Catheter in patients with a clot in the heart resulting in a heart attack.
Principal Investigator: Larry Diaz, MD
Find this study on clinicaltrials.gov: https://clinicaltrials.gov/ct2/show/NCT03957473?term=A+Prospective%2C+Multicenter+Study+to+Evaluate+the+Safety+and+Performance+of+the+CAT+RX+Aspiration+Catheter+in+Patients+with+a+High+Thrombus+Burden+Acute+Coronary+Vessel+Occlusion&draw=2&rank=1

HERITAGE: Multi-center, cross-sectional, epidemiological study to characterize the prevalence and distribution of lipoprotein(a) levels among patients with established cardiovascular disease
Condition: Heart Attack, Stroke, or Peripheral Vascular Disease
The purpose of this research is to determine if patients have an elevated lipoprotein(a) lab value.
Principal Investigator: Rony Gorges, MD
Find this study on clinicaltrials.gov: https://clinicaltrials.gov/ct2/show/NCT03887520?term=Multi-center%2C+cross-sectional%2C+epidemiological+study+to+characterize&draw=2&rank=1

PULMONOLOGY

CHRONICLE: A Longitudinal Prospective Observational Study of the Characteristics, Treatment Patterns and Health Outcomes of Individuals with Severe Asthma in the United States
Condition: Severe Asthma
The purpose of this registry is to collect information on patient characteristics, treatment patterns, and health outcomes in patients with severe asthma.
Investigator: Gregory Neagos, MD
Find this study on clinicaltrials.gov: https://clinicaltrials.gov/ct2/show/NCT03373045?term=chronicle&draw=2&rank=5

KNOCOUT PE: Retrospective and Prospective International EkoSonic Registry of the Treatment and Clinical Outcomes of Patients With Pulmonary Embolism
Condition: Pulmonary Embolism
The purpose of this registry is to determine the treatment regimens used globally for EkoSonic therapy.
Investigator: Larry Diaz, MD
Find this study on clinicaltrials.gov: https://clinicaltrials.gov/ct2/show/NCT03426124?term=Retrospective+and+Prospective+International+EkoSonic+Registry+of+the+Treatment+and+Clinical+Outcomes+of+Patients+With+Pulmonary+Embolism&draw=2&rank=1

SLEEP

remede System Therapy Registry (reST Registry)
Condition: Central Sleep Apnea
The purpose of this registry is to collect safety and effectiveness data in participants with central sleep apnea implanted with the remede System.
Investigator: Matthew Sevensma, DO
Find this study on clinicaltrials.gov: https://clinicaltrials.gov/ct2/show/NCT03884660?term=remede+system+therapy+registry&draw=2&rank=1